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We used the following 5 search strategies to keep away from bias retrieval of searching solely major journals and to obtain gray literature (e.g., abstracts, unpublished studies).10 First, the next digital databases were searched: AMED, CINAHL, The Cochrane Library, EMBASE, MEDLINE, PubMed, and threonine price Web of Science. Each database was searched from inception up until February 2013. The digital databases have been looked for title and abstract using the important thing phrases outlined in Onakpoya et al.6 Second, ancestry searches (ie, treeing backward) had been conducted utilizing the reference lists of all located clinical studies. Third, we contacted lively researchers in the sector to retrieve either current or unpublished analysis. Fourth, computerized author database searches have been performed on all authors of retrieved studies assembly the inclusion criteria. Finally, manufacturers of commercial GCBE merchandise had been contacted to determine printed and unpublished materials. Solely articles revealed in English have been reviewed.

The obvious lack of side effects of glutamine supplementation shouldn’t be surprising, considering the abundance of glutamine within the human physique. Serum levels of glutamine are within the vary of 390-650 mg/dl for adults, compared to 18-98 range for glutamate. Children have higher upper values for each glutamate and glutamine (140 and 730 mg/dl).

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