Nutrition as well as diet – Vitamin B6


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Vitamin B6 occurs in three forms–pyridoxine, pyridoxamine, and pyridoxal. B6 is absorbed in the massive intestine. The muscle stores more or less 75-80 % of the vitamin even though the live stores about 5-10 %.

B6 is necessary for transaminations, decarboxylations, dehydratases, side chain cleavage reactions, alpilean reviews amazon and ammonia release. The aldehyde group of its acts as a Schiff base to act in response with the amino groups of amino acids. It basically acts to shuttle nitrogen among compounds.

Functions- The 3 forms of B6 could all be converted on the coenzyme PLP which aids in transamination & protein metabolism. PLP is important for glycogen degradation; it may also help with the formation of the neurotransmitter, serotonin, the nonprotein part of hemoglobin (heme), nucleic acids, and lecithin. Vitamin B6 is important for the metabolic process of tryptophan to niacin.

Overall Reactions:

· Transaminations These reactions are necessary to reuse as well as reuse nitrogen in the human body. They are the first stage in amino acid catabolism as well as the last step in the synthesis of nonessential amino acids. Example: a-ketoglutarate + asparate glutamate + oxaloacetate

· Serine/ Threonine Deamination (Dehydratases) This reaction has the generation of the a keto acids of threonine as well as serine through oxidative removal of N as ammonia Example: Serine a-keto-serine + NH4+

· Decarboxylation These reactions typically occur on the neuroactive amines of seratonin, tyramine, histamine, and GABA. Additionally they are critical in porphyrin synthesis, intermediates in the synthesis of sphingomyelin, taurine and lecithin, and for the description as well as desulfuration of cysteine.

· Glycogen Phosphorylase fifty % of all B6 in the body is certain to glycogen phosphorylase though the importance is unknown. The reaction is crucial for recycling of folate and is as follows:

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