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Outcomes: Discount in arterial stiffness was observed after 12 months of equol supplement (1402.Three cm/s vs.1367.Three cm/s, p < 0.001). Significant reductions in respective parameters were observed in women with moderate and high risk for arteriosclerosis (median [95% confidence interval]: -3.2% [-5.79 to -0.74]; -12.65% [-18.52 to -4.28]; respectively); hypertriglyceridemia -45.53% [-70.24 to -5.58]; bone resorption risk (-15.15% [-23.71 to 1.56]; and bone fracture risk -26.68% [-76.43 to -5.99]. All 15 women with high baseline parathyroid hormone levels had achieved a median of 50% [-54.11 to -31.69] reduction from their baseline values. These associations were further confirmed in the results of multiple linear regression analysis. There were no reported adverse events or abnormal findings in the blood chemistry, Pap smear, mammography, and transvaginal ultrasound during periodic follow-ups.

there are a few which have some supportive evidence for managing menopause signs together with black cohosh, soy isoflavones and crimson clover extract (and naturally, calcium and vitamin d for bone health), however it is necessary to chat with your healthcare provider first before taking them because some of these could trigger interactions with different.

Serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) were estimated by enzymatic strategies utilizing the kit supplied by Erba Mannheim®, Brno, エクオール（及びエクオール　サプリ） CZ, (Tietz et al., 2012). Low-density lipoprotein cholesterol (LDL-C) was calculated in accordance with Friedewald equation: LDL-C (mg/dl) = TC − HDL-C−TG/5 (Friedewald et al. 1972). Non-HDL-C = (TC) − (HDL-C) danger issue = (TC)/(HDL-C).